SULT1E1 anticorps (AA 100-294)
Aperçu rapide pour SULT1E1 anticorps (AA 100-294) (ABIN7858989)
Antigène
Voir toutes SULT1E1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 100-294
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Fonction
- Sulfotransferase family 1E, estrogen-preferring, member 1 Antibody
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Specificité
- The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. SULT1E1, also known as STE, is a 294 amino acid member of the SULT1 family. Localized to the cytoplasm and expressed in intestine, liver and kidney, SULT1E1 exists as a homodimer that is thought to control estrogen receptor (ER) levels by sulfurylating free estradiol. Defects in the gene encoding SULT1E1 are associated with an increased risk for endometrial cancer, suggesting a role for SULT1E1 in tumorigenesis.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa100-294) of human SULT1E1 protein (exact sequence is proprietary)
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Isotype
- IgG2, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))
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Autre désignation
- Sulfotransferase family 1E, estrogen-preferring, member 1
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Sujet
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EST, EST-1,EST1, Estrogen sulfotransferase, estrogen-preferring, estrone sulfotransferase, ST1E1, STE, Sulfotransferase 1E1, Sulfotransferase , Sulfotransferase estrogen preferring
HEPG2 cells. Human liver|intestine or kidney.
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Poids moléculaire
- 35kDa
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ID gène
- 6783, 479898
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UniProt
- P49888
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Pathways
- Steroid Hormone Biosynthesis
Antigène
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