Luteinizing Hormone anticorps (AA 100-300)
Aperçu rapide pour Luteinizing Hormone anticorps (AA 100-300) (ABIN7859024)
Antigène
Voir toutes Luteinizing Hormone (LH) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 100-300
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Fonction
- Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR) Antibody
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Specificité
- Recognizes a protein of 78-85 kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa 100-300) of human LHCGR protein (exact sequence is proprietary)
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Isotype
- IgG2, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Luteinizing Hormone (LH)
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Autre désignation
- Luteinizing Hormone
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Classe de substances
- Hormone
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Sujet
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Gonadotropin receptor, GTHR-II, HHG, LCGR, LGR2, LH-R, LH/CG-R, LH/CGR, LHCGR, LHR, LHRHR, LSH-R, Luteinizing hormone receptor, Luteinizing hormone/choriogonadotropin receptor, Lutropin choriogonadotropic receptor, Lutropin-choriogonadotropic hormone receptor, ULG5
HepG2 or Jurkat cells. Human ovarian carcinoma.
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Poids moléculaire
- 78-85kDa
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ID gène
- 3973, 468490
Antigène
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