MUC13 anticorps (AA 100-300)
Aperçu rapide pour MUC13 anticorps (AA 100-300) (ABIN7859026)
Antigène
Voir toutes MUC13 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 100-300
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Fonction
- MUC13 / Mucin 13 Antibody
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Specificité
- Mucins are epithelial glycoproteins with a high content of clustered oligosaccharides that are O-glycoside linked to tandem repeat peptides rich in threonine, serine and proline. Mucin 13 (MUC13), also designated downregulated in colon cancer 1 (DRCC1), is an epithelial and hemopoietic type I membrane protein that undergoes secretion and influences gastrointestinal mucosa levels. It is most abundant in epithelial tissues of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. Mucin 13 is a good differentiation marker for gastrointestinal mucosa and may also indicate certain gastric tumors. It localizes to the apical membrane of both columnar and goblet cells in the gastrointestinal tract, and within goblet cell thecae. Mucin 13 is a cleaved protein, and the b subunit, containing the cytoplasmic tail, can homodimerize.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa100-300) of human MUC13 protein (exact sequence is proprietary)
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- MUC13 (Mucin 13, Cell Surface Associated (MUC13))
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Autre désignation
- MUC13
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Sujet
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DRCC1, MUC-13
Human colon or small intestine.
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Poids moléculaire
- 58kDa
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ID gène
- 56667, 514227
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UniProt
- Q9H3R2
Antigène
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