Uroplakin 3B anticorps (AA 100-300)
Aperçu rapide pour Uroplakin 3B anticorps (AA 100-300) (ABIN7859044)
Antigène
Voir toutes Uroplakin 3B (UPK3B) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 100-300
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Fonction
- Uroplakin 3B (UPK3B) (Marker of Mesothelial &, Umbrella Cells) Antibody
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Specificité
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa 100-300) of human Uroplakin 3B (UPK3B) protein (exact sequence is proprietary)
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Uroplakin 3B (UPK3B)
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Autre désignation
- Uroplakin 3B
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Sujet
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FLJ32198, MGC10902, p35, UP3b, UPIIIb, UPK3B, UPK3B_HUMAN, uroplakin 3B, Uroplakin IIIb, Uroplakin-3b
Human urinary bladder.
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Poids moléculaire
- 32kDa
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ID gène
- 105375355, 488861
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UniProt
- Q9BT76
Antigène
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