Recombinant VWF anticorps (AA 1150-1250)

N° du produit ABIN7863886

Cet anticorps Lapin Monoclonal détecte spécifiquement VWF dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant VWF anticorps (AA 1150-1250) (ABIN7863886)

Antigène: VWF (Von Willebrand Factor (VWF))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp VWF est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: VWF-7979R

Détail du produit anti-VWF anticorps

Épitope: AA 1150-1250

Fonction: Recombinant von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Antibody

Specificité: Human von Willebrand factor (VWF or factor VIII-related antigen) is a 309 kDa multimeric plasma glycoprotein, important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Von Willebrand factor also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. Von Willebrand factor is synthesized by endothelial cells and is reported to be expressed in a number of tumors of vascular origin. IHC results aid in the classification of acute myeloid leukemia FAB type M7, angiosarcoma and epithelioid hemangioendothelioma.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 1150-1250) of human vWF protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur VWF

Antigène: VWF (Von Willebrand Factor (VWF))

Autre désignation: von Willebrand Factor

Sujet:

Coagulation Factor VIII, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)

Human tonsil.

Poids moléculaire: 250kDa

ID gène: 7450, 440848

UniProt: P04275