Paired Box 3 anticorps (AA 150-350)

N° du produit ABIN7864185

L’anticorps anti-Paired Box 3 Monoclonal Souris est utilisé pour la détection de Paired Box 3 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Paired Box 3 anticorps (AA 150-350) (ABIN7864185)

Antigène: Paired Box 3 (PAX3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Paired Box 3 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: PAX3-8426

Détail du produit anti-Paired Box 3 anticorps

Épitope: AA 150-350

Fonction: PAX3 Antibody

Specificité: Pax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa150-350) of human PAX3 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Paired Box 3

Antigène: Paired Box 3 (PAX3)

Autre désignation: PAX3

Sujet:

CDHS, HUP2, Paired box 3, Paired box homeotic gene 3, Paired box protein Pax 3, Paired domain gene HuP2, PAX3/FKHR fusion gene, Sp, splotch, Waardenburg syndrome 1, WS1, WS3

Human skin and skeletal muscle tissue.

Poids moléculaire: 56kDa

ID gène: 5077, 42146

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation