AMBP anticorps (AA 200-353)

N° du produit ABIN7864718

Cet anticorps anti-AMBP Monoclonal Souris (Clone AMBP-4533) (ABIN7864718) détecte spécifiquement AMBP dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour AMBP anticorps (AA 200-353) (ABIN7864718)

Antigène: AMBP (alpha 1 Microglobulin/bikunin precursor (AMBP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AMBP est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: AMBP-4533

Détail du produit anti-AMBP anticorps

Épitope: AA 200-353

Fonction: AMBP (Alpha 1 Microglobulin) / Bikunin Antibody

Specificité: The AMBP (±-1-Microglobulin/Bikunin precursor) gene encodes a protein precursor, known as AMBP, that is cleaved to produce two distinct proteins, designated ±-1-Microglobulin and Bikunin. ±-1-Microglobulin, also known as protein HC, is a member of the lipocalin superfamily and is secreted mainly in plasma, urine and cerebrospinal fluid. Thought to have reductase/dehydrogenase activity, ±-1-Microglobulin exhibits immunosuppressive properties, such as cytokine secretion and inhibition of antigen-induced lymphocyte cell proliferation, and may be involved in the reduction of biological pro-oxidants. The second protein cleavage product, designated Bikunin and also known as inter-±-trypsin inhibitor light chain, ITI-LC or urinary trypsin inhibitor, is a widely expressed protein that is stored in the granules of human connective tissue mast cells. One of many proteins in the Kunitz-type protease inhibitor family, Bikunin prevents autodigestion by exocrine enzymes, such as trypsinogen and chymo-trypsinogen, and plays a role in the antiinflammatory/antiproteinase immune response. Unlike ±-1-Microglobulin, Bikunin is implicated in the pathogenesis of a number of renal diseases, such as urolithiasis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa200-353) of human AMBP protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur AMBP

Antigène: AMBP (alpha 1 Microglobulin/bikunin precursor (AMBP))

Autre désignation: AMBP

Sujet:

A1M, Alpha 1 microglobulin/bikunin precursor, Alpha 1 microglycoprotein, Bikunin, Complex-forming glycoprotein heterogeneous in charge, EDC1, Growth inhibiting protein 19, HCP, HI30, IATIL, ITI, ITI-LC, ITIL, Microglobulin (alpha 1), Protein AMBP, Protein HC, Trypstatin, Uristatin, Uronic-acid-rich protein, UTI

Human liver or placenta.

Poids moléculaire: 30kDa

ID gène: 259, 436911