Galectin 9 anticorps (AA 200-355)

N° du produit ABIN7865471

Cet anticorps Souris Monoclonal détecte spécifiquement Galectin 9 dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Galectin 9 anticorps (AA 200-355) (ABIN7865471)

Antigène: Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Galectin 9 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: LGALS9-7689

Détail du produit anti-Galectin 9 anticorps

Épitope: AA 200-355

Fonction: Galectin-9 (LGALS9) (Marker of T-Cell Exhaustion) Antibody

Specificité: Galectins are a family of soluble ≤-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One member of this family, Galectin-9, also known as Ecalectin, Gal-9, hUAT2, HOM-HD-21 or LGALS9, maps to human chromosome 17 and encodes a 36 kDa protein. Galectin-9 is an integral membrane protein that exists as two isoforms, a long form and a short form, which differ by an internal stretch of 32 amino acids. Galectin-9 is an eosinophile chemoattractant produced by activated T lymphocytes that is expressed in organs of the gastrointestinal tract, aorta, liver, kidney, liver, pancreatic islets, lung, tonsil and some colorectal carcinoma, and in the cell lines HUVEC, U-937, HL60, HeLa and Jurkat. Introduction of IL-1beta enhances Galectin-9 expression. Increased expression of Galectin-9 induces apoptosis in thymocytes and CD8+ cells. Galectin-9 is involved in immuno/inflammation processes in potential-sensitive uric acid translocation and contributes to inflammatory reactions in the central nervous system (CNS).

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa200-355) of human LGALS9 protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Galectin 9

Antigène: Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))

Autre désignation: Galectin-9

Sujet:

Gal-9 | LGALS9

Human lung, liver, breast or kidney.

Poids moléculaire: 36kDa

ID gène: 3965

UniProt: O00182