BTBD9 anticorps (AA 200-400)

N° du produit ABIN7859463

L’anticorps anti-BTBD9 Monoclonal Souris est utilisé pour la détection de BTBD9 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour BTBD9 anticorps (AA 200-400) (ABIN7859463)

Antigène: BTBD9 (BTB (POZ) Domain Containing 9 (BTBD9))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BTBD9 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: BTBD9-7501

Détail du produit anti-BTBD9 anticorps

Épitope: AA 200-400

Fonction: BTBD9 Antibody

Specificité: BTBD9 (BTB/POZ domain-containing protein 9) is a 612 amino acid protein that contains one BTB/POZ domain and one BACK (BTB/Kelch associated) domain. The BTB/POZ domain mediates homomeric and heteromeric POZPOZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including Bcl-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD9 may play a role in transcription regulation. Genetic variations in the gene that encodes BTBD9 have been associated with susceptibility to restless legs syndrome type 6 (RLS6), a condition characterized by an uncontrollable urge to move the legs while resting.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa200-400) of human BTBD9 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur BTBD9

Antigène: BTBD9 (BTB (POZ) Domain Containing 9 (BTBD9))

Autre désignation: BTBD9

Sujet:

BTB/POZ domain-containing protein 9

Human fallopian tube|lung or lymph node.

Poids moléculaire: 69kDa

ID gène: 114781, 603858

UniProt: Q96Q07

Pathways: Transition Metal Ion Homeostasis