Apolipoprotein D anticorps (AA 21-119)

N° du produit ABIN7862974

Cet anticorps Souris Monoclonal détecte spécifiquement Apolipoprotein D dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Apolipoprotein D anticorps (AA 21-119) (ABIN7862974)

Antigène: Apolipoprotein D (APOD)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Apolipoprotein D est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: APOD-3412

Détail du produit anti-Apolipoprotein D anticorps

Épitope: AA 21-119

Fonction: Apolipoprotein D / APOD Antibody

Specificité: Lipids, such as phospholipids, triacylglycerols and cholesterol, are weakly soluble in aqueous solution and therefore are transported by circulation as components of lipoproteins. Lipoproteins are globular particles that consist of a non-polar core of triacylglycerols and cholesteryl esters surrounded by phospholipid, cholesterol and an amphiphilic coating of protein, known as apolipoproteins (apo). These complexes allow the dissolution and shuttling of their non-polar lipid components. At least nine different apolipoproteins are distributed in significant amounts in different human lipoproteins. Apolipoprotein D (apoD) is a member of the lipocalin superfamily of transporter proteins that bind small hydrophobic molecules, including arachidonic acid (AA). The ability of apoD to bind AA implicates it in pathways associated with membrane phospholipid signal transduction and metabolism. apoD expression has been shown to correlate both with cell cycle arrest and with prognosis in several types of malignancy, including central nervous system astrocytomas and medulloblastomas.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Human recombinant APOD protein fragment (around aa 21-119) (exact sequence is proprietary)

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Apolipoprotein D

Antigène: Apolipoprotein D (APOD)

Autre désignation: Apolipoprotein D

Sujet:

APO-D protein

Human colon and breast cancer tissues.

Poids moléculaire: 30kDa

ID gène: 347, 522555

UniProt: P05090

Pathways: Platelet-derived growth Factor Receptor Signaling