Recombinant Decorin anticorps (AA 212-336)

N° du produit ABIN7859540

Cet anticorps Lapin Monoclonal détecte spécifiquement Decorin dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant Decorin anticorps (AA 212-336) (ABIN7859540)

Antigène: Decorin (DCN)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Decorin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: DCN-8760R

Détail du produit anti-Decorin anticorps

Épitope: AA 212-336

Fonction: Recombinant Decorin Antibody

Specificité: Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as Fibronectin and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGF≤ and is a direct or indirect negative modulator of TGF≤ synthesis. Inhibition of Decorin core protein gene expression by the combination of IFN-≥ and TNF± may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. For immunostaining, pre-incubation with chondroitinase-SBC or testicular hyaluronidase may be required to expose the epitope.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human Decorin protein fragment (around aa212-336) (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Decorin

Antigène: Decorin (DCN)

Autre désignation: Decorin

Sujet:

Bone proteoglycan II, CSCD, Dermatan sulphate proteoglycans II (DSPG2), PG40, PGII, PGS2, Proteoglycan core protein, SLRR1B, Small leucine rich protein 1B

Human prostate or skin tissue (IHC). Heart, Lung, Skeletal muscle.

Poids moléculaire: 43kDa

ID gène: 1634, 728830

Pathways: Glycosaminoglycan Metabolic Process