CDH6 anticorps (AA 250-450)

N° du produit ABIN7859646

L’anticorps anti-CDH6 Monoclonal Souris est utilisé pour la détection de CDH6 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour CDH6 anticorps (AA 250-450) (ABIN7859646)

Antigène: CDH6 (K-Cadherin (CDH6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDH6 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: CDH6-9347

Détail du produit anti-CDH6 anticorps

Épitope: AA 250-450

Fonction: Cadherin-6 (CDH6) / K-Cadherin Antibody

Specificité: This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. This protein may play a role in kidney development as well as endometrium and placenta formation. Decreased expression of this gene may be associated with tumor growth and metastasis.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 250-450) of human Cadherin 6 protein (CDH6) (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur CDH6

Antigène: CDH6 (K-Cadherin (CDH6))

Autre désignation: Cadherin-6

Sujet:

Cadherin-6, CDH6, CAD6, KCAD,

Human kidney or renal cell carcinoma.

Poids moléculaire: 130kDa

ID gène: 1004, 124776

UniProt: P55285

Pathways: Cell-Cell Junction Organization