RBP4 anticorps (AA 29-148)

N° du produit ABIN7863339

L’anticorps anti-RBP4 Monoclonal Souris est utilisé pour la détection de RBP4 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour RBP4 anticorps (AA 29-148) (ABIN7863339)

Antigène: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RBP4 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: RBP4-4049

Détail du produit anti-RBP4 anticorps

Épitope: AA 29-148

Fonction: RBP4 / Retinol Binding Protein 4 Antibody

Specificité: Retinol (Vitamin A) is transported in the blood bound to its carrier protein, retinol-binding protein (RBP), also designated plasma retinol-binding protein (PRBP) or RBP4. A member of the lipocalin family, RBP conveys retinol from stores in the liver to peripheral tissues. In plasma, RBP binds transthyretin (TTR, formerly called prealbumin) to prevent glomerular filtration of low molecular weight RBP in the kidneys. The stability of this complex holds diagnostic importance because the molar ratio of RBP:TTR provides an indirect way to indicate marginal Vitamin A deficiency. Vitamin A deficiency blocks the secretion of RBP, resulting in defective delivery and supply to epidermal cells. Originally identified solely as a transporter protein, recent studies correlating increased levels of RBP expression in adipose tissue with Insulin resistance have generated research into the possible roles the protein may play in the pathogenesis of type 2 diabetes and obesity.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa29-148) of human RBP4 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide store at 2 to 8 °C. Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur RBP4

Antigène: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Autre désignation: RBP4

Sujet:

Plasma retinol binding protein 4 (PRBP), RDCCAS, Retinol binding protein 4 interstitial

HeP-G2 cells. Human kidney, pancreas or liver tissues.

Poids moléculaire: 25kDa

ID gène: 5950, 50223

UniProt: P02753

Pathways: Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response