ENPP3 anticorps (AA 300-600)
Aperçu rapide pour ENPP3 anticorps (AA 300-600) (ABIN7859854)
Antigène
Voir toutes ENPP3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 300-600
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Fonction
- CD203c / ENPP3 (Basophil Marker) Antibody
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Specificité
- Ecto-nucleotide pyrophosphatase/phosphodiesterase-I enzymes (E-NPP), a group of type II transmembrane proteins, cleave phosphodiester and phosphosulfate bonds in deoxynucleotides, NAD, and nucleotide sugars. There exist three closely related proteins in mammalian species: E-NPP1 (PC-1), E-NPP2 (PDNP2), and E-NPP-3, also known as CD203c, each expressed in different cells or at different locations in the same cells. Basophils, a type of major proinflammatory effector cells involved in diverse pathologic reactions, exhibit CD203c expression. For instance, CD203c expression increases in response to a variety of allergens, including cat dander, latex, and bee and wasp venom. Hovever, these allergies are not the only condition associated with CD203c upregulation, CD203c upregulation may also serve as a tumor marker for colon carcinoma.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa300-600) of human ENPP3 protein (exact sequence is proprietary)
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Isotype
- IgG, kappa
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- ENPP3 (Ectonucleotide pyrophosphatase/phosphodiesterase 3 (ENPP3))
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Autre désignation
- CD203c
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Sujet
- B10, NPP3, PDNP3, CD203c, PD-IBETA
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Poids moléculaire
- 100kDa
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ID gène
- 5169, 486489
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UniProt
- O14638
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Pathways
- Regulation of Muscle Cell Differentiation, Negative Regulation of Transporter Activity
Antigène
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