Vitamin D-Binding Protein anticorps (AA 35-175)

N° du produit ABIN7862887

L’anticorps anti-Vitamin D-Binding Protein Monoclonal Souris est utilisé pour la détection de Vitamin D-Binding Protein dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Vitamin D-Binding Protein anticorps (AA 35-175) (ABIN7862887)

Antigène: Vitamin D-Binding Protein (GC)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Vitamin D-Binding Protein est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: VDBP-4481

Détail du produit anti-Vitamin D-Binding Protein anticorps

Épitope: AA 35-175

Fonction: GC Vitamin D Binding Protein Antibody

Specificité: Vitamin D-binding protein (DBP) is a multi-functional serum protein that binds to the plasma membranes of numerous cell types and mediates a variety of cellular functions. The locus of the DBP protein (also known as group-specific component protein or GC) is located at human chromosome 4q13.3. DBP functions in organ-specific transportation of vitamin D and its metabolites to the various target organs of the vitamin D endocrine system. In addition, DBP has immunomodulatory properties and is able to bind to the surface of leukocytes. DBP binds to the plasma membrane through a chondroitin sulfate proteoglycan. DBP serves as a co-chemotactic factor for C5a to enhance the chemotactic activity of C5a. DBP can also bind to globular Actin with high affinity and is involved in the clearance of Actin from the blood. DBP plays an important role in osteoclast differentiation. The diverse cellular functions of DBP require its cell surface binding ability to mediate different biological processes.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 35-175) of human GC protein (exact sequence is proprietary)

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Vitamin D-Binding Protein

Antigène: Vitamin D-Binding Protein (GC)

Autre désignation: GC Vitamin D Binding Protein

Sujet:

DBP/GC, Gc globulin, GRD3, Group specific component vitamin D binding protein, hDBP, VDB, VDBG, VDBP, Vitamin D binding alpha globulin, Vitamin D-binding protein

Human liver, kidney or pancreas.

Poids moléculaire: 53kDa.

ID gène: 2638, 418497

UniProt: P02774

Pathways: Metabolism of Steroid Hormones and Vitamin D, Monocarboxylic Acid Catabolic Process