Factor VII anticorps (AA 366-466)

N° du produit ABIN7864702

Cet anticorps anti-Factor VII Monoclonal Souris (Clone F7-3515) (ABIN7864702) détecte spécifiquement Factor VII dans IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Factor VII anticorps (AA 366-466) (ABIN7864702)

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Factor VII est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: F7-3515

Détail du produit anti-Factor VII anticorps

Épitope: AA 366-466

Fonction: Coagulation Factor VII / F7 Antibody

Specificité: Hemostasis following tissue injury involves the deployment of essential plasma procoagulants (prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade that leads to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Coagulation Factor VII (serum prothrombin conversion accelerator, proconvertin, F7, Factor VII) is a 406 amino acid, vitamin K-dependent, single chain serine protease that is synthesized in the liver and circulates as an inactive precursor. Factor IX A, Factor X A, Factor XII A or Thrombin-mediated proteolytic cleavage of Factor VII at Arg 152-Ile 153 generates Factor VII A, an active serine protease composed of a catalytic heavy chain disulfide linked to a light chain, containing two EGF-like domains. Mutations at the F7 locus that lead to Factor VII deficiencies are generally asymptomatic or phenotypically uncharacterized, with hemorrhagic diathesis occurring at extremely low levels.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 366-466) of human F7 protein

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Factor VII

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Autre désignation: Coagulation Factor VII

Sujet:

Eptacog alfa, Factor VII heavy chain, Factor VII light chain, FVII coagulation protein, Proconvertin, Serum prothrombin conversion accelerator (SPCA)

Human liver or gastric carcinoma.

Poids moléculaire: 200/80/73/50/43 kDa

ID gène: 2155, 36989

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling