Recombinant Keratin 6 anticorps (AA 400-564)

N° du produit ABIN7863971

L’anticorps anti-Keratin 6 Monoclonal Lapin est utilisé pour la détection de Keratin 6 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant Keratin 6 anticorps (AA 400-564) (ABIN7863971)

Antigène: Keratin 6 (KRT6)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Keratin 6 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: RKRT6-9402

Détail du produit anti-Keratin 6 anticorps

Épitope: AA 400-564

Fonction: Recombinant Cytokeratin 6 / KRT6 (Pan, a,b,c) (Basal Cell Marker) Antibody

Specificité: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16.Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa400-564) of human KRT6 (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Keratin 6

Antigène: Keratin 6 (KRT6)

Autre désignation: Cytokeratin 6

Sujet:

CK6A, CK6B, CK6C, CK6D, CK6E, Keratin Type II Cytoskeletal 6A, Keratin Type II Cytoskeletal 6B, Keratin Type II

Human tonsil or basal cell carcinoma (BCC).

Poids moléculaire: 56kDa

ID gène: 3853, 700779

UniProt: P02538