CD56 anticorps (AA 400-650)
Aperçu rapide pour CD56 anticorps (AA 400-650) (ABIN7860121)
Antigène
Voir toutes CD56 (NCAM1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 400-650
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Fonction
- CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Antibody
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Specificité
- This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa400-650) of human NCAM1 protein (exact sequence is proprietary)
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- CD56 (NCAM1) (Neural Cell Adhesion Molecule 1 (NCAM1))
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Autre désignation
- CD56
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Sujet
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NCAM, Leu-19, NKH1, MSK39, NCAM120, NCAM140, NCAM180, Neural Cell Adhesion Molecule
Human cerebellum, pancreas or neuroblastoma.
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Poids moléculaire
- 180, 145 and 125kDa
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ID gène
- 4684, 503878
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UniProt
- P13591, P13592
Antigène
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