CEACAM1 anticorps (AA 50-250)

N° du produit ABIN7860219

L’anticorps anti-CEACAM1 Monoclonal Souris est utilisé pour la détection de CEACAM1 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour CEACAM1 anticorps (AA 50-250) (ABIN7860219)

Antigène: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CEACAM1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: CEACAM1-4840

Détail du produit anti-CEACAM1 anticorps

Épitope: AA 50-250

Fonction: CEACAM1 (CEA Cell Adhesion Molecule 1) Antibody

Specificité: Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constantlike A and/or B domains. CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1), also known as BGP or BGP1, is a 526 amino acid protein that exists as seven alternatively spliced isoforms, some of which localize to the cell membranes, while others are secreted. One of several members of the CEACAM family, CEACAM1 contains one Ig-like V-type domain and three Ig-like C2-type domains and is thought to play a role in a variety of cellular activities, including angiogenesis, apoptosis, arrangement of tissue threedimensional structure and modulation of innate and adaptive immune responses. Additionally, CEACAM1 is underexpressed in colorectal cancers, suggesting a role in tumor suppression.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa 50-250) of human CEACAM1 protein (exact sequence is proprietary)

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur CEACAM1

Antigène: CEACAM1 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1))

Autre désignation: CEACAM1

Sujet:

Antigen CD66, BGP-1, BGPI, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), CD66a, CEACAM1, meconium antigen 100

endometrium|Human: colon|liver or hepatic carcinoma tissues.

Poids moléculaire: 90-180kDa

ID gène: 634, 512682

UniProt: P13688