CD207 anticorps (AA 50-250)

N° du produit ABIN7864472

Cet anticorps anti-CD207 Monoclonal Souris (Clone LGRN-7429) (ABIN7864472) détecte spécifiquement CD207 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CD207 anticorps (AA 50-250) (ABIN7864472)

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD207 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: LGRN-7429

Détail du produit anti-CD207 anticorps

Épitope: AA 50-250

Fonction: Langerin / CD207 (Marker of Langerhans Cells) Antibody

Specificité: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa50-250) of human Langerin protein (exact sequence is proprietary)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur CD207

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Autre désignation: Langerin

Sujet:

C-type lectin domain family 4 member K, CD207, CLEC4K, Langerhans cell specific c type lectin, Langerin

Human skin.

Poids moléculaire: 48kDa

ID gène: 50489, 199731

UniProt: Q9UJ71