Elastase 3A anticorps (AA 50-250)
Aperçu rapide pour Elastase 3A anticorps (AA 50-250) (ABIN7865399)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 50-250
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Fonction
- CELA3A / Chymotrypsin like elastase 3A Antibody
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Specificité
- Elastases belong to a subfamily of serine proteases that function to catalytically hydrolyze a wide variety of proteins. Elastase-3A, also known as ELA3A or ELA3, is a 270 amino acid protein that belongs to the elastase family and acts as an alanine-specific protease. Secreted as a zymogen from the pancreas, Elastase-3A functions as a digestive enzyme in the intestine that participates in metabolic degradation pathways by preferentially cleaving proteins that have alanine residues. In addition, Elastase-3A is thought to play a role in the metabolism and transport of cholesterol molecules in the intestine. Altered expression of Elastase-3A may be associated with pancreatic ductal carcinoma, a highly fatal cancer of the pancreatic ducts
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa50-250) of human CELA3A protein (exact sequence is proprietary)
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Isotype
- IgG1, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Elastase 3A (ELA3A)
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Autre désignation
- CELA3A
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Sujet
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ELA3, ELA3A
Human pancreas or pancreatic cancer.
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Poids moléculaire
- 29 kDa
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ID gène
- 10136
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UniProt
- P09093
Antigène
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