TGFB3 anticorps (AA 50-250)

N° du produit ABIN7860277

Cet anticorps anti-TGFB3 Monoclonal Souris (Clone TGFB3-4801) (ABIN7860277) détecte spécifiquement TGFB3 dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour TGFB3 anticorps (AA 50-250) (ABIN7860277)

Antigène: TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TGFB3 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: TGFB3-4801

Détail du produit anti-TGFB3 anticorps

Épitope: AA 50-250

Fonction: TGFB3 / PEIG-1 / RAI3 / RAIG1 / TIG1 Antibody

Specificité: Transforming growth factor ≤s (TGF≤s) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGF≤. TGF≤1, TGF≤2 and TGF≤3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. TGF≤3 mediates many intercellular interactions that occur during embryonic development, cell differentiation and epithelial homeostasis. TGF≤3 overexpresses in extramammary Paget s disease (EPD) and downregulates in Bowen s disease, indicating that its expression is a useful indicator of tumor activity. TGF≤3 levels strongly correlate with IGF-1 and osteocalcin levels in serum. Significant amounts of TGF≤3 circulation appear to be representative of TGF≤3 expression in bone and may in part be derived from bone. Glucocorticoids may block TGF≤ production by modulating mRNA levels and c-Jun activity.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa50-250) of human TGFB3 protein (exact sequence is proprietary)

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur TGFB3

Antigène: TGFB3 (Transforming Growth Factor, beta 3 (TGFB3))

Autre désignation: TGFB3

Sujet:

ARVD1, LDS5, prepro-transforming growth factor beta-3, RNHF, TGFB 3, Tgfb3, transforming growth factor beta 3

heart or lung.|Human kidney

Poids moléculaire: 13kDa

ID gène: 7043, 592317

UniProt: P10600

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus