Recombinant Villin 1 anticorps (AA 600-700)
Aperçu rapide pour Recombinant Villin 1 anticorps (AA 600-700) (ABIN7863495)
Antigène
Voir toutes Villin 1 (VIL1) AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 600-700
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Fonction
- Recombinant Villin (GI-Mucosal & Urogenital Brush Border Marker) Antibody
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Specificité
- Recognizes a protein of 95 kDa, which is identified as villin. It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, villin is predominantly expressed in tumors of colorectal origin. Antibody to villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant fragment (around aa600-700) of human Villin protein (exact sequence is proprietary)
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Isotype
- IgG, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Villin 1 (VIL1)
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Autre désignation
- Villin
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Sujet
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VIL1, Villin-1, Villin1
A549, HepG2 or HCT116 cells. Human colon or rectum.
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Poids moléculaire
- 93kDa
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ID gène
- 7429, 654595
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UniProt
- P09327
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Pathways
- EGFR Signaling Pathway, Regulation of Actin Filament Polymerization
Antigène
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