Recombinant RRM1 anticorps (AA 700-800)

N° du produit ABIN7863356

Cet anticorps Lapin Monoclonal détecte spécifiquement RRM1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant RRM1 anticorps (AA 700-800) (ABIN7863356)

Antigène: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp RRM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RRM1-4372R

Détail du produit anti-RRM1 anticorps

Épitope: AA 700-800

Fonction: Recombinant Ribonucleotide Reductase M1 / RRM1 Antibody

Specificité: Ribonucleotide reductase M1 polypeptide (RRM1) is one of two non-identical subunits for ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is present throughout the cell division cycle but downregulated in quiescent cells. RRM1 is involved in carcinogenesis, tumor progression, and the response of non-small-cell lung cancer (NSCLC) to chemotherapy.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Synthetic peptide corresponding to residues within aa700-800 of human RRM1 (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur RRM1

Antigène: RRM1 (Ribonucleotide Reductase M1 (RRM1))

Autre désignation: Ribonucleotide Reductase M1

Sujet:

Ribonucleoside diphosphate reductase large subunit, Ribonucleoside diphosphate reductase M1 chain, RR1, RRM1, RIR1, Ribonucleotide reductase M1 polypeptide, Ribonucleotide reductase R1 subunit

Human breast, lung or colon carcinoma tissue. Human Intestine, Human Skin, A549, HEK293 or K-562

Poids moléculaire: 94kDa

ID gène: 6240, 445705

Pathways: Positive Regulation of Endopeptidase Activity