Inhibin alpha anticorps (AA 73-96)
Aperçu rapide pour Inhibin alpha anticorps (AA 73-96) (ABIN7863028)
Antigène
Voir toutes Inhibin alpha (INHA) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 73-96
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Fonction
- Inhibin, alpha (INHA) (Gonadal Cell Marker) Antibody
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Specificité
- It recognizes a 47 kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same °™ subunit, covalently linked to 1 of 2 distinct subunits, æ-°™ or æ- æ. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, inhibin belongs to the transforming growth factor æ (TFG æ) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- A synthetic peptide (around aa73-96) of α-subunit of human inhibin A protein (exact sequence is proprietary)
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Inhibin alpha (INHA) (Inhibin, alpha (INHA))
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Autre désignation
- Inhibin, alpha
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Sujet
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A inhibin subunit, IHA, inhA, Inhibin alpha chain, Inhibin alpha subunit
Human prostate or testis.
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Poids moléculaire
- 47kDa
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ID gène
- 3623, 407506
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UniProt
- P05111
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Pathways
- Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion
Antigène
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