VWF anticorps (AA 845-949)

N° du produit ABIN7860643

Cet anticorps anti-VWF Monoclonal Souris (Clone VWF-4105) (ABIN7860643) détecte spécifiquement VWF dans IHC. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour VWF anticorps (AA 845-949) (ABIN7860643)

Antigène: VWF (Von Willebrand Factor (VWF))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VWF est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: VWF-4105

Détail du produit anti-VWF anticorps

Épitope: AA 845-949

Fonction: von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Antibody

Specificité: Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi s sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human vWF fragment spanning around aa 845-949 (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur VWF

Antigène: VWF (Von Willebrand Factor (VWF))

Autre désignation: von Willebrand Factor

Sujet:

Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)

HUVEC cells. Human tonsil or uterus.

Poids moléculaire: 250kDa

ID gène: 7450, 440848

UniProt: P04275