Liver Arginase anticorps (Arg1)
Aperçu rapide pour Liver Arginase anticorps (Arg1) (ABIN7860678)
Antigène
Voir toutes Liver Arginase (ARG1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 11-97, Arg1
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Fonction
- Arginase 1 (Hepatocellular Carcinoma Marker) Antibody
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Specificité
- Recognizes a protein of 35-38 kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant human ARG1 protein fragment (around aa11-97) (exact sequence is proprietary)
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Isotype
- IgG2a, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Liver Arginase (ARG1) (Arginase, Liver (ARG1))
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Autre désignation
- Arginase 1
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Sujet
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Arginase 1, ARG1, liver-type arginase, type I arginase
Human Liver, Mouse Liver, Rat Liver, Hamster Liver or Guinea pig Liver
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Poids moléculaire
- 35-38kDa
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ID gène
- 383, 440934
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UniProt
- P05089
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Antigène
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