Paired Box 3 anticorps (C-Term)
Aperçu rapide pour Paired Box 3 anticorps (C-Term) (ABIN7860714)
Antigène
Voir toutes Paired Box 3 (PAX3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- C-Term
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Fonction
- PAX3 Antibody
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Specificité
- Pax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Synthetic peptide (quail) from the C-terminus
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Isotype
- IgG2a, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- Paired Box 3 (PAX3)
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Autre désignation
- PAX3
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Sujet
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CDHS, HUP2, Paired box 3, Paired box homeotic gene 3, Paired box protein Pax 3, Paired domain gene HuP2, PAX3/FKHR fusion gene, Sp, splotch, Waardenburg syndrome 1, WS1, WS3
Human skin and skeletal muscle tissue.
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Poids moléculaire
- 56kDa
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ID gène
- 5077, 42146
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UniProt
- P23760
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Pathways
- Sensory Perception of Sound, Tube Formation
Antigène
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