Recombinant Filaggrin anticorps (N-Term)

N° du produit ABIN7860789

L’anticorps anti-Filaggrin Monoclonal Souris est utilisé pour la détection de Filaggrin dans des échantillons de Humain. Il a été validé pour IHC et WB.

Aperçu rapide pour Recombinant Filaggrin anticorps (N-Term) (ABIN7860789)

Antigène: Filaggrin (FLG)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Filaggrin est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Clone: R15C10

Détail du produit anti-Filaggrin anticorps

Épitope: N-Term

Fonction: Recombinant Filaggrin (Keratinocyte Differentiation Marker) Antibody

Specificité: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules.Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Prokaryotic recombinant protein corresponding to a portion of the N-terminus of the human filaggrin molecule

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Filaggrin

Antigène: Filaggrin (FLG)

Autre désignation: Filaggrin

Sujet:

ATOD2, Epidermal Filaggrin, Filaggrin, Filaggrin precursor, Fillagrin, FLG, Profilaggrin

Human skin.

Poids moléculaire: 26-45kDa (Processed), 350kDa (Profilaggrin)

ID gène: 2312, 654510

UniProt: P20930

Pathways: Sensory Perception of Sound, Stem Cell Maintenance