Recombinant Parvin, beta anticorps (N-Term)

N° du produit ABIN7860822

L’anticorps anti-Parvin, beta Monoclonal Lapin est utilisé pour la détection de Parvin, beta dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant Parvin, beta anticorps (N-Term) (ABIN7860822)

Antigène: Parvin, beta (PARVB)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Parvin, beta est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: PARVB-8214R

Détail du produit anti-Parvin, beta anticorps

Épitope: AA 1-91, N-Term

Fonction: Recombinant Beta-Parvin Antibody

Specificité: Beta-parvin, also known as affixin, is a focal adhesion protein belonging to a family of ILKbinding proteins that contain tandem calponin homolog domains. Along with Alpha-parvin, Beta-parvin is one of the most widely researched and characterized members of this family. These two proteins interact with the ILK kinase domain in a way that is mutually exclusive and regulates both the activity of the kinase and actin cytoskeleton adhesion. Studies have shown Beta-parvin to be downregulated within human breast cancer cells, and that its expression may influence the progression of breast cancer (Johnstone, 2008). Additional research indicates a critical role for Beta-parvin in the regulation of cardiac contractility when it is in complex with ILK (Hannigan, 2007).

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: N-terminal region (residues 1-91) of human b-parvin

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Parvin, beta

Antigène: Parvin, beta (PARVB)

Autre désignation: Beta-Parvin

Sujet:

Affixin, beta-parvin, CGI-56, Parvb

HeLa cell lysate. HeLa cells. Human stomach.

Poids moléculaire: 41kDa

ID gène: 29780, 475074

UniProt: Q9HBI1