AMACR anticorps

N° du produit ABIN7860889

Cet anticorps anti-AMACR Monoclonal Souris (Clone AMACR-4757) (ABIN7860889) détecte spécifiquement AMACR dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour AMACR anticorps (ABIN7860889)

Antigène: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp AMACR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: AMACR-4757

Détail du produit anti-AMACR anticorps

Fonction: AMACR / p504S (Prostate Cancer Marker) Antibody

Specificité: This antibody recognizes a protein of 42 kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and ≤-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human AMACR protein

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur AMACR

Antigène: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Autre désignation: AMACR

Sujet:

Alpha-methylacyl-CoA Racemase, CBAS4, Da1-8, Macr1, RACE, RM

liver or prostate adenocarcinoma.|PC3 or HEK cells. Human kidney

Poids moléculaire: 42kDa

ID gène: 23600, 508343

UniProt: Q9UHK6

Pathways: Monocarboxylic Acid Catabolic Process