BCL6 anticorps

N° du produit ABIN7863352

L’anticorps anti-BCL6 Monoclonal Souris est utilisé pour la détection de BCL6 dans des échantillons de Humain. Il a été validé pour FACS et IF.

Aperçu rapide pour BCL6 anticorps (ABIN7863352)

Antigène: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL6 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: PCRP-BCL6-1E2

Détail du produit anti-BCL6 anticorps

Fonction: BCL6 Antibody

Specificité: Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( L&H ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human BCL6 protein

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur BCL6

Antigène: BCL6 (B-Cell CLL/lymphoma 6 (BCL6))

Autre désignation: BCL6

Sujet:

B-cell lymphoma 5 protein (BCL5), B-Cell Lymphoma 6 Protein, BCL6A, cys his2 zinc finger transcription factor, Lymphoma Associated Zinc Finger Gene On Chromosome 3 (LAZ3), Zinc finger and BTB domain-containing protein 27 (ZBTB27), Zinc Finger Protein 51 (ZNF51), zinc finger transcription factor BCL6S

HeLa or MCF-7 cells.

Poids moléculaire: 95kDa

ID gène: 604, 478588

UniProt: P41182

Pathways: Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus