CRYAB anticorps

N° du produit ABIN7861149

L’anticorps anti-CRYAB Monoclonal Souris est utilisé pour la détection de CRYAB dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour CRYAB anticorps (ABIN7861149)

Antigène: CRYAB (Crystallin, alpha B (CRYAB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CRYAB est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: CRYAB-7917

Détail du produit anti-CRYAB anticorps

Fonction: Crystallin Alpha B Antibody

Specificité: Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into ±, ≤ and ≥ families, and the ≤- and ≥-crystallins also compose a superfamily. Crystallins usually contain seven distinct protein regions, including four homologous motifs, a connecting peptide and N- and C-terminal extensions. ±-crystallins consist of three gene products, ±A-, ±B- and ±C-crystallin, which are members of the small heat shock protein family (HSP 20). ±-crystallins act as molecular chaperones by holding denatured proteins in large soluble aggregates. However, unlike other molecular chaperones, ±-crystallins do not renature these proteins. Expression of ±A-crystallin is restricted to the lens and defects of this gene cause the development of autosomal dominant congenital cataracts (ADCC). The human ±B-crystallin gene product is expressed in many tissues, including lens, heart and skeletal muscle. Elevated expression of ±B-crystallin is associated with many neurological diseases, and a missense mutation in this gene has co-segregated in a family with a Desmin-related myopathy.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human full-length CRYAB protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur CRYAB

Antigène: CRYAB (Crystallin, alpha B (CRYAB))

Autre désignation: Crystallin Alpha B

Sujet:

AACRYA, Alpha B crystallin, Alpha-crystallin B chain, CRYA2, CTTP2, Heat shock 20 kD like protein, Heat shock protein beta-5, HspB5, Renal carcinoma antigen NY REN 27, Rosenthal fiber component

Human heart, kidney or brain.

Poids moléculaire: Predicted: 20kDa, Observed: 22-30kDa

ID gène: 1410, 53454

UniProt: P02511