DAXX anticorps

N° du produit ABIN7861202

Cet anticorps Souris Monoclonal détecte spécifiquement DAXX dans IHC et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour DAXX anticorps (ABIN7861202)

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DAXX est non-conjugé

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: PCRP-DAXX-6E11

Détail du produit anti-DAXX anticorps

Fonction: DAXX (Transcriptional Corepressor) Antibody

Specificité: This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human DAXX protein

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur DAXX

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Autre désignation: DAXX

Sujet:

DAP6, EAP1, BING2, SMIM40

HeLa or U87 cells. Ubiquitous tissue expression.

Poids moléculaire: 81.37kDa

ID gène: 1616, 336916

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway