Decorin anticorps

N° du produit ABIN7862693

L’anticorps anti-Decorin Monoclonal Souris est utilisé pour la détection de Decorin dans des échantillons de Humain, Souris, Boeuf (Vache), Chien, Lapin, Porc, Cheval, Poulet et Élan. Il a été validé pour WB, IHC, IF et FACS.

Aperçu rapide pour Decorin anticorps (ABIN7862693)

Antigène: Decorin (DCN)

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Lapin, Porc, Cheval, Poulet, Élan

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Decorin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: DCN-6289

Détail du produit anti-Decorin anticorps

Fonction: Decorin / PGS2 Antibody

Specificité: Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein contains ten leucine rich repeats that contain sites for glycosylation, flanked by disulfide bond stabilizing loops. Decorin binds to Collagen Type I, II and IV in vivo and promotes the formation of fibers with variations in stability and solubility. The Decorin core protein binds to growth factors, intercellular matrix molecules, such as Fibronectin and Thrombospondin, and to the Decorin endocytosis receptor. Decorin binds to and inhibits TGF æ and is a direct or indirect negative modulator of TGF æ synthesis. Inhibition of Decorin core protein gene expression by the combination of IFN-Á and TNF°™ may contribute to cartilage destruction that is characteristic of inflammatory joint diseases. For immunostaining, pre-incubation with chondroitinase-SBC or testicular hyaluronidase may be required to expose the epitope.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length DCN protein

Isotype: IgG1, lambda

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Decorin

Antigène: Decorin (DCN)

Autre désignation: Decorin

Sujet:

Bone proteoglycan II, CSCD, Dermatan sulphate proteoglycans II (DSPG2), PG40, PGII, PGS2, Proteoglycan core protein, SLRR1B, Small leucine rich protein 1B

Prostate or skin tissue.

Poids moléculaire: 43kDa

ID gène: 1634, 728830

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process