Recombinant EGFRviii anticorps

N° du produit ABIN7862726

Cet anticorps Lapin Monoclonal détecte spécifiquement EGFRviii dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Recombinant EGFRviii anticorps (ABIN7862726)

Antigène: EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp EGFRviii est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: GFR-2600R

Détail du produit anti-EGFRviii anticorps

Fonction: Recombinant EGFRvIII (Epidermal Growth Factor Receptor, Variant III) Antibody

Specificité: EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogène: KLH conjugate of EGFRvIII-specific, 14-amino acid peptide from the predicted amino acid sequence at the fusion junction (LEEKKGNYVVTDHC)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur EGFRviii

Antigène: EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))

Autre désignation: EGFRvIII

Sujet:

Erbb1 variant III, ERBB1 variant III, HER1 variant III, Proto-oncogene c-ErbB-1 variant III, Receptor Tyrosine Protein Kinase variant III, ErbB1 variant III

A431 cells. Placenta, Breast, Colon or Bladder Carcinoma

Poids moléculaire: ~145kDa (vIII variant)

ID gène: 1956, 488293

UniProt: P00533