Endoglin anticorps

N° du produit ABIN7863922

Cet anticorps anti-Endoglin Monoclonal Souris (Clone ENG-4750) (ABIN7863922) détecte spécifiquement Endoglin dans IHC. L’anticorps est réactif avec des échantillons de Humain, Rat, Porc, Cheval et Singe.

Aperçu rapide pour Endoglin anticorps (ABIN7863922)

Antigène: Endoglin (ENG)

Reactivité: Humain, Rat, Porc, Cheval, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Endoglin est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: ENG-4750

Détail du produit anti-Endoglin anticorps

Fonction: Endoglin / CD105 (Angiogenesis Marker) Antibody

Specificité: CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for Prostate Adenocarcinoma, and cancers of the lung, stomach, breast, and brain.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant extracellular fragment of human Endoglin protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Endoglin

Antigène: Endoglin (ENG)

Autre désignation: Endoglin

Sujet:

CD105, END, Endoglin, Eng, HHT1, S-endoglin

A431 or HL-60 cells.|HeLa

Poids moléculaire: 80kDa (Monomer), 160kDa (Homodimer)

ID gène: 2022, 76753