ERG anticorps
Aperçu rapide pour ERG anticorps (ABIN7862751)
Antigène
Voir toutes ERG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- ERG / ETS Transcription Factor (Prostate Cancer Marker) Antibody
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Specificité
- The transcription factor erythroblastosis virus E26 transforming sequence related gene (ERG) functions as a regulator of key cellular functions to promote endothelial homeostasis.Expression of ERG has been observed in both benign and malignant vascular endothelial tumors, such as hemangiomas and Kaposi sarcomas, respectively.Carcinomas of the breast, colon, and urothelium have demonstrated absence of ERG expression, whereas presence of the protein has been confirmed in a subset of prostate carcinoma cases.Anti-ERG can be a useful tool for identifying vascular endothelial neoplasms and distinguishing prostate carcinoma from epithelial tumors of non-prostatic origin.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant human full-length ERG protein
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- ERG (ERG, ETS transcription factor (ERG))
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Autre désignation
- ERG
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Sujet
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ERG, ERG/EWS fusion gene, ERG/FUS fusion gene, ERG/TMPSSR2 fusion gene, ERG1, ETS-related, KCNH2, Oncogene ERG, p55, TMPRSS2/ERG fusion
Ewing sarcoma or prostate adenocarcinoma tissues., HUVEC cells. Human tonsil
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Poids moléculaire
- 55kDa
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ID gène
- 2078, 473819
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UniProt
- P11308
Antigène
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