Recombinant RCAS1 anticorps

N° du produit ABIN7861287

L’anticorps anti-RCAS1 Monoclonal Souris est utilisé pour la détection de RCAS1 dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant RCAS1 anticorps (ABIN7861287)

Antigène: RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RCAS1 est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: REBAG9-7264

Détail du produit anti-RCAS1 anticorps

Fonction: Recombinant RCAS1 / Estrogen Receptor Binding Site Associated, Antigen 9 Antibody

Specificité: EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human EBAG9 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur RCAS1

Antigène: RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))

Autre désignation: RCAS1

Sujet:

BAG9, cancer associated surface antigen, cancer associated surface antigen RCAS1, EB9, estrogen receptor binding fragment associated gene 9, PDAF, receptor binding cancer antigen expressed on SiSo cells

Jurkat or HEK-293 cell lysates. Human skeletal muscle tissue.|MCF-7

Poids moléculaire: 32kDa

ID gène: 9166, 409368

UniProt: O00559