EIF4A2 anticorps

N° du produit ABIN7862734

Cet anticorps anti-EIF4A2 Monoclonal Souris (Clone PCRP-EIF4A2-2B5) (ABIN7862734) détecte spécifiquement EIF4A2 dans ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour EIF4A2 anticorps (ABIN7862734)

Antigène: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF4A2 est non-conjugé

Application: ELISA

Clone: PCRP-EIF4A2-2B5

Détail du produit anti-EIF4A2 anticorps

Fonction: EIF4A2 (Eukaryotic Initiation Factor 4A-II) Antibody

Specificité: Translation initiation in eukaryotes necessitates the assembly of an 80S ribosomal complex. Eukaryotic initiation factors (eIFs) are utilized in a sequence of reactions that leads to 80S ribosomal assembly and initiation of translation. Mammalian eukaryotic translation initiation factor 4F (eIF4F) is a protein complex that contains eIF4A, eIF4E and eIF4G, binds mRNA at a5'-cap motif and recruits the 43S ribosomal preinitiation complex to the eligible transcript. Along with eIF4B, the eIF4F complex mediates the unwinding of mRNA secondary structure to facilitate ribosome association. eIF4E specifically interacts with the 5' cap, eIF4A (I, II) are bidirectional RNA helicases, and eIF4G (I, II) are scaffolding proteins which coordinate eIF4E, eIF4A, eIF3and the 40S ribosome. Human eIF4AI (eIF4A, DDX2A) is a 406 amino acid protein that is 92.7% homologous to mouse eIF4AI. The promoter region of human eIF4A1 contains TATA and CAAT motifs and consensus binding sites to Sp1 and AP2.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human EIF4A2 protein

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur EIF4A2

Antigène: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Autre désignation: EIF4A2

Sujet:

ATP dependent RNA helicase eIF4A 2, BM-010, DDX2B, EIF4F, eukaryotic translation initiation factor 4A isoform 2, N-terminally processed

HeLa cells.

Poids moléculaire: 46kDa

ID gène: 1974

UniProt: Q14240