Recombinant GATA3 anticorps

N° du produit ABIN7861335

L’anticorps anti-GATA3 Monoclonal Souris est utilisé pour la détection de GATA3 dans des échantillons de Humain et Rat. Il a été validé pour WB et IHC.

Aperçu rapide pour Recombinant GATA3 anticorps (ABIN7861335)

Antigène: GATA3 (GATA Binding Protein 3 (GATA3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GATA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: RGATA3-3870

Détail du produit anti-GATA3 anticorps

Fonction: Recombinant GATA-3 (Breast and Urothelial Marker) Antibody

Specificité: GATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50 kDa nuclear protein regulates the development and subsequent maintenance of a variety of human tissues, including hematopoietic cells, skin, kidney, mammary gland, and the central nervous system. Among several other roles, GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67 % of urothelial Carcinomas, but none of prostate or renal carcinomas.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human GATA-3 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur GATA3

Antigène: GATA3 (GATA Binding Protein 3 (GATA3))

Autre désignation: GATA-3

Sujet:

GATA3, GATA binding protein-3, GATA-binding factor 3, GATA3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3

Human breast or urothelial carcinoma tissue. Jurkat.

Poids moléculaire: ~50kDa

ID gène: 2625, 524134

UniProt: P23771

Pathways: Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation