GTF2IRD2 anticorps
Aperçu rapide pour GTF2IRD2 anticorps (ABIN7861390)
Antigène
Voir toutes GTF2IRD2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- GTF2IRD2 Antibody
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Specificité
- The TFII-I family contains two highly homologous 949 amino acid proteins, GTF2IRD2 (GTF2I repeat domain containing 2) and GTF2IRD2B (general transcription factor II-I repeat domain-containing protein 2B). Localizing to the nucleus, these proteins are ubiquitously expressed and contain two GTF2I- like repeats. Encoded by a gene mapping to human chromosome 7q11.23, GTF2IRD2 and GTF2IRD2B are located in the Williams-Beuren syndrome (WBS) critical region. The deletion of genes located within this region results in WBS, possibly due to the unequal crossing over of highly homologous low-copy repeat sequences that flank the deleted region. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits including facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant full-length human GTF2IRD2 protein
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- GTF2IRD2 (GTF2I Repeat Domain Containing 2 (GTF2IRD2))
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Autre désignation
- GTF2IRD2
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Sujet
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FP630, GTF2IRD2A, GTF2IRD2 alpha
HeLa or K562 cells.
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Poids moléculaire
- 107kDa
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ID gène
- 84163, 647039
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UniProt
- Q86UP8
Antigène
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