Recombinant IgD anticorps

N° du produit ABIN7863859

L’anticorps anti-IgD Monoclonal Lapin est utilisé pour la détection de IgD dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour Recombinant IgD anticorps (ABIN7863859)

Antigène: IgD

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp IgD est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: IGHD-2730R

Détail du produit anti-IgD anticorps

Fonction: Recombinant IgD (Immunoglobulin Delta Heavy Chain) (B-Cell Marker) Antibody

Specificité: Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with é 79oΩ heavy chains and either é 79oΩ or é 79oΩ light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human IGHD protein

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur IgD

Antigène: IgD

Autre désignation: IGHD

Sujet:

Ig delta chain C region, IGHD, Immunoglobulin heavy constant delta

Human tonsil lysate or NAMALWA cell lysate. Human tonsil and lymphoid tissues. Human Serum

Poids moléculaire: 44-80kDa (heavy chain), 21-25kDa (kappa light chain)

ID gène: 3495, 510635

UniProt: P01880