IgD anticorps

N° du produit ABIN7861494

L’anticorps anti-IgD Monoclonal Souris est utilisé pour la détection de IgD dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour IgD anticorps (ABIN7861494)

Antigène: IgD

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IgD est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: IGHD-4967

Détail du produit anti-IgD anticorps

Fonction: IgD (Immunoglobulin Delta Heavy Chain) (B-Cell Marker) Antibody

Specificité: Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through interchain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin D (IgD) exists as a monomer with t heavy chains and either é 79oΩ or é 79oΩ light chains. It plays a biological role as a transmembrane receptor molecule, co-expressed with IgM on the surface of mature/naive B cells. In particular, it is found on spleen B cell surfaces. Compared to IgM, IgD exists in much lower numbers and is not expressed on immature B cells. IgD surface expression on B cells is regulated in part by IL-27. In mice, the inhibition of this immunoglobulin isotype does not cause a significant change to the immune system.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Full-length human IGHD protein

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur IgD

Antigène: IgD

Autre désignation: IGHD

Sujet:

Ig delta chain C region, IGHD, Immunoglobulin heavy constant delta

Human tonsil lysate, NAMALWA cell lysate, Human tonsil and lymphoid tissues

Poids moléculaire: 44-80kDa (heavy chain), 21-25kDa (kappa light chain)

ID gène: 3495, 510635