IGF2BP2 anticorps
Aperçu rapide pour IGF2BP2 anticorps (ABIN7861504)
Antigène
Voir toutes IGF2BP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- IGF2BP2 Antibody
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Specificité
- IGF2BP2 (Insulin-like growth factor 2 mRNA binding protein 2) is also known as IGF2 mRNA-binding protein 2, IMP-2 (IGF-II mRNA-binding protein 2), VICKZ family member 2 or hepatocellular carcinoma autoantigen p62 and is a 556 amino acid protein. IGF2BP2 is expressed in a variety of tissues including heart, placenta, skeletal muscle, pancreas, fetal liver, lung, kidney, thymus and gonadal cells. IGF2BP2 is an RNA binding protein which may be involved in the regulation of mRNA translation and may also function to control the spatial localization of target mRNAs. Antibodies against IGF2BP2 have been detected in patients with HCC (hepatocellular carcinoma), suggesting that IGF2BP2 may have a role in the pathogenesis of HCC. Defects in IGF2BP2 are thought to be associated with susceptibility to type two diabetes mellitus.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant full-length human IGF2BP2 protein
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Isotype
- IgG2, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Date de péremption
- 24 months
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- IGF2BP2 (Insulin-Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2))
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Autre désignation
- IGF2BP2
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Sujet
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Hepatocellular carcinoma autoantigen p62, IGF 2 mRNA binding protein 2, IGF II mRNA binding protein 2, IMP2, Insulin like growth factor 2 mRNA binding protein 2, p62, VICKZ 2, VICKZ family member 2, VICKZ2
HeLa cells.
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Poids moléculaire
- 105kDa
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ID gène
- 10644, 35354
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UniProt
- Q9Y6M1
Antigène
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