HDAC6 anticorps (pSer22) (Cy5)

N° du produit ABIN742992

Cet anticorps anti-HDAC6 est un anticorps Lapin Polyclonal détectant HDAC6 dans WB, IF (cc) et IF (p). Adapté pour Humain.

Aperçu rapide pour HDAC6 anticorps (pSer22) (Cy5) (ABIN742992)

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC6 est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-HDAC6 anticorps (Cy5)

Épitope: pSer22

Réactivité croisée: Humain

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human HDAC6 around the phosphorylation site of Ser22

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HDAC6

Antigène: HDAC6 (Histone Deacetylase 6 (HDAC6))

Autre désignation: HDAC6

Sujet:

Synonyms: HDAC6 phospho S22, HDAC6 phospho Ser22, p-HDAC6 Ser22, HD 6, HD6, HDAC 6, Histone deacetylase 6, HD6, Histone deacetylase 6, JM 21, JM21, KIAA0901, FLJ16239, HDAC6_HUMAN.

Background: HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation.

ID gène: 10013

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling