Recombinant MUC16 anticorps

N° du produit ABIN7865447

Cet anticorps anti-MUC16 Monoclonal Lapin (Clone CA125-9923R) (ABIN7865447) détecte spécifiquement MUC16 dans IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant MUC16 anticorps (ABIN7865447)

Antigène: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC16 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Clone: CA125-9923R

Détail du produit anti-MUC16 anticorps

Fonction: Recombinant MUC16 / CA125 (Ovarian Carcinoma Marker) Antibody

Specificité: CA125 also known as mucin 16, is a member of the mucin family glycoproteins. CA125 is a component of the ocular surface (including the cornea and conjunctiva), the respiratory tract and the female reproductive tract epithelia. Since CA125 is highly glycosylated it creates a hydrophilic environment that acts as a lubricating barrier against foreign particles and infectious agents on the apical membrane of epithelial cells. CA125 reacts with both normal tissues and neoplasms of fallopian tube, endometrium, endocervix and mesothelioma. It does not react with colon cancer. Normal tissues such as breast, liver, skin, kidney and spleen are also negative. Studies have shown that CA125 reacts with approximately 80 % of epithelial ovarian neoplasms of serous, endometrioid, clear cell and undifferentiated types. No reactivity has been shown for mucinous ovarian tumors or in germ cell or hematopoietic tumors. This antibody is a useful aid for classification of a variety of tumors, such as some adenocarcinomas of the colon, breast carcinomas, malignant mesothelioma, uterine adenomatoid tumor, lung bronchoalveolar carcinoma, and ovarian endometrioid and serous carcinomas.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human MUC16 protein

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur MUC16

Antigène: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Autre désignation: MUC16

Sujet:

CA125, Cancer antigen 125, MUC16, Mucin16, Ovarian cancer-related tumor marker CA125

MDA-MB-468 cells. Ovarian Cancer.

Poids moléculaire: >2000kDa

ID gène: 94025, 432676

UniProt: Q8WXI7