Recombinant Periostin anticorps

N° du produit ABIN7861905

L’anticorps anti-Periostin Monoclonal Lapin est utilisé pour la détection de Periostin dans des échantillons de Humain. Il a été validé pour IHC.

Aperçu rapide pour Recombinant Periostin anticorps (ABIN7861905)

Antigène: Periostin (POSTN)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Periostin est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: POSTN-8951R

Détail du produit anti-Periostin anticorps

Fonction: Recombinant Periostin (POSTN) Antibody

Specificité: Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for ±V≤3 and ±V≤5 integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor ≤ 1 (TGF ≤ 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment of human POSTN protein (exact sequence is proprietary)

Isotype: IgG, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Periostin

Antigène: Periostin (POSTN)

Autre désignation: Periostin

Sujet:

Fasciclin-I like, Osteoblast specific factor 2 (OSF2), PDLPOSTN, Periodontal ligament specific periostin, Periostin isoform thy2 / th4 / thy6 / thy8, Periostin osteoblast specific factor, PN, POSTN

breast or colon tissue.|Human placenta

Poids moléculaire: 84/74kDa (Periostin), 90kDa (secreted glycoprotein)

ID gène: 10631, 136348, 721018

UniProt: Q15063