POGZ anticorps
Aperçu rapide pour POGZ anticorps (ABIN7864446)
Antigène
Voir toutes POGZ AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- POGZ Antibody
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Specificité
- This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
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Purification
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogène
- Recombinant full-length human POGZ protein
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Isotype
- IgG2b
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- POGZ (Pogo Transposable Element with ZNF Domain (POGZ))
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Autre désignation
- POGZ
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Sujet
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KIAA0461, ZNF280E, ZNF635m, Pogo transposable element with ZNF domain
HeLa or U87 cells. Human placenta|tonsil or colon.
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Poids moléculaire
- 155.3kDa
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ID gène
- 23126, 25040
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UniProt
- Q7Z3K3
Antigène
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