QKI anticorps

N° du produit ABIN7863633

L’anticorps anti-QKI Monoclonal Souris est utilisé pour la détection de QKI dans des échantillons de Humain. Il a été validé pour WB, IF, ELISA et FACS.

Aperçu rapide pour QKI anticorps (ABIN7863633)

Antigène: QKI (Protein Quaking (QKI))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp QKI est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)

Clone: PCRP-QKI-2F10

Détail du produit anti-QKI anticorps

Fonction: QKI / Protein Quaking Antibody

Specificité: QKI, also known as HKQ, QK, QK3 or quaking, is a 341 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one KH domain. Expressed in the frontal cortex of the brain, QKI functions as an RNA-binding protein that plays an important role in myelinization and specifically binds to the RNA core sequence 5'-NACUAAY-N(1,20)-UAAY-3'. Additionally, QKI regulates pre-mRNA splicing, and mRNA export and is involved in protecting and promoting the stability of select mRNAs. QKI may be methylated by PRMT1 and may also be phosphorylated at its C-terminus, an event that decreases QKI mRNA-binding affinity. Defects or deletions in the gene encoding QKI are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Multiple isoforms of QKI exist due to alternative splicing events.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant full-length human QKI protein

Isotype: IgG2c

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur QKI

Antigène: QKI (Protein Quaking (QKI))

Autre désignation: QKI

Sujet:

Homolog of mouse quaking QKI KH domain RNA binding protein, HQK1, Protein quaking, QK1, QK3, QKI, QKI1, Quaking homolog KH domain RNA binding mouse, Quaking isoform 1, Quaking protein, RNA binding protein HQK

HeLa, K562 or MCF7 cells., U87

Poids moléculaire: 37.6kDa

ID gène: 9444, 510324

UniProt: Q96PU8